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FAQ: Understanding the Link Between Uterine Fibroids and Heart Disease Risk
TL;DR
Women with uterine fibroids can gain a health advantage by proactively managing heart disease risk, as a new study shows their long-term risk is over 80% higher.
A 10-year study of 2.7 million women found those with uterine fibroids had an 81% higher cardiovascular disease risk, with the strongest association in women under age 40.
This research helps make tomorrow better by identifying fibroids as a marker for heart disease risk, enabling earlier preventive care and conversations about women's cardiovascular health.
Uterine fibroids, affecting up to 80% of women by age 50, are now linked to significantly increased heart disease risk across all racial groups.
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Women diagnosed with uterine fibroids have more than 80% higher long-term heart disease risk compared to women without fibroids, according to a 10-year study of over 2.7 million U.S. women.
The risk is substantial - after 10 years of follow-up, more than 5.4% of women with fibroids had experienced a cardiovascular event compared to 3% of women without fibroids, representing an 81% higher risk.
Researchers monitored for coronary artery disease (including heart attack), cerebrovascular disease (stroke and related conditions), and peripheral artery disease over the 10-year follow-up period.
The research was conducted by Julia D. DiTosto, M.S., a Ph.D. Candidate in Epidemiology at the Perelman School of Medicine at the University of Pennsylvania, and published in the Journal of the American Heart Association.
According to the U.S. Office of Women's Health, as many as 20% to 80% of women will develop fibroids by the time they reach age 50, with nearly 26 million pre-menopausal women in the U.S. impacted.
Some studies have shown that fibroids and cardiovascular disease share biological pathways, including the growth of smooth muscle cells, excessive buildup of fibrous connective tissue, calcification, and inflammatory responses.
Yes, the elevated heart disease risk persisted among all races and ages studied, but was particularly strong in women younger than 40.
The findings suggest women diagnosed with fibroids may benefit from enhanced attention to heart health and risk factor management, as fibroids may serve as an important marker for identifying women at elevated cardiovascular risk.
Previous studies on this topic have been hindered by limitations including small study sample sizes that lacked diversity and insufficient study design, which this research aimed to address with a large, diverse dataset.
Researchers said more studies are needed to better understand and confirm the relationship between having uterine fibroids and increased heart disease risk.
Curated from NewMediaWire
