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Klotho Conference 2025 FAQ: Key Insights on Klotho Research, Therapies, and Diagnostics
TL;DR
The Klotho Conference showcased new therapeutic approaches like mRNA-LNP that could give companies a first-mover advantage in the emerging longevity market.
Researchers presented Klotho's molecular pathways, clinical translation progress, and diagnostic advances from 4,390 published papers to actionable healthspan extension strategies.
Klotho research advances could extend healthy aging, reduce age-related diseases, and improve quality of life for millions through regenerative therapies.
The Klotho gene discovered in 1997 now shows potential for reversing aging effects from brain health to organ regeneration.
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The conference brought together leading researchers, clinicians, and innovators to discuss the most recent Klotho biology research, its therapeutic potential, and diagnostic advances, with the goal of translating decades of Klotho research into actionable strategies for healthspan extension.
The conference was held September 15–16, 2025 at the UCI Beall Applied Innovation Center in Irvine, California.
Key speakers included Dr. Makoto Kuroo (who discovered the Klotho gene), Carmela Abraham (presented Klotho-mRNA-LNP approach), Dr. Dena Dubal and Dr. Miguel Chillon (discussed Klotho's neuroprotective role), Dr. Ido Wolf and Dr. Tamar Rubinek (presented on Klotho and cancer), and Dr. Assumpció Bosch (discussed Klotho gene therapy for ALS).
The conference covered state of the industry and foundational science, new Klotho therapeutic modalities, human case studies and clinical insights, Klotho and brain health, Klotho and cancer, gene therapy for longevity diseases, and inflammation, aging & Klotho.
Carmela Abraham presented results of a Klotho-mRNA-LNP approach to increasing Klotho levels, and Dr. Assumpció Bosch discussed Klotho gene therapy for ALS with preclinical progress and future clinical trial roadmaps.
A short highlight reel is available at https://youtu.be/ngH6qERXwRI and a playlist of ALL Klotho Conference Presentations in full is available at https://www.youtube.com/playlist?list=PLIzjBuzofFehaUfXU0GdvI2X8cr3gm6SY.
This landmark event marked a significant step forward in translating decades of Klotho research into actionable strategies for healthspan extension by bringing together global experts to accelerate Klotho-based therapies and diagnostics.
More information about the conference agenda can be found at https://klothoconference.com/agenda/.
Curated from Newsworthy.ai

