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FAQ: South Fork Instruments' Kemtrak UV Spectra Process Analyzer for Real-Time Deep-UV Measurement
TL;DR
South Fork Instruments' Kemtrak UV Spectra Process Analyzer provides bioprocessing teams with reliable inline data and multi-wavelength capability for competitive advantage in demanding purification steps.
The analyzer uses a mercury-free UV-xenon light source with up to 10 user-selectable wavelengths from 190-440 nm and zero-dead-volume cells for precise real-time absorbance measurement.
This technology enables more efficient biochemical production and process monitoring, potentially accelerating development of pharmaceuticals and treatments to improve healthcare outcomes worldwide.
South Fork's new analyzer measures proteins, mRNA, and APIs with deep-UV photometry using materials like sapphire and titanium for industrial applications.
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The Kemtrak UV Spectra Process Analyzer is a multi-wavelength deep-UV photometer designed for real-time absorbance measurement of proteins, peptides, polypeptides, mRNA/DNA, amino acids, APIs, and process intermediates, providing high-resolution continuous absorbance measurement from 190 to 440 nm.
According to John Daly, Technical Director at South Fork Instruments, bioprocessing teams are working with higher concentrations and more demanding purification steps, and the Kemtrak UV Spectra provides the deep-UV performance, zero-dead-volume measurement, and verification tools needed to generate reliable inline data for chromatography, filtration, and high-value process streams.
Key features include multi-wavelength deep-UV absorbance measurement from 190-440 nm with up to 10 user-selectable wavelengths, ±0.005 AU photometric resolution, 10 Hz sampling frequency, zero-dead-volume hygienic measurement cells, a mercury-free UV-xenon light source with up to two years of continuous operation, and integrated traceable verification with NIST-compliant reference standards.
The system integrates zero-dead-volume hygienic measurement cells available in stainless steel, titanium, Hastelloy, Monel, PTFE, and PPSU, with window options in sapphire and UV-fused silica, and wetted surfaces available with electropolished finishes down to Ra _ 0.38 μm.
The analyzer supports applications in chromatography, filtration, biochemical production, and process monitoring, particularly for real-time inline monitoring of high-value process streams in bioprocessing and industrial settings.
South Fork Instruments is an established supplier of measurement instrumentation, analyzers, and control products based in Auburn, California, serving the Americas across industries including chemical plants, breweries, refineries, mining, power generation, food processing, offshore/onshore oil production, and pipelines.
The analyzer features integrated traceable verification with NIST-compliant reference standards and a verification port, along with high-stability optical measurement, ±0.005 AU photometric resolution, and fast 10 Hz sampling for continuous real-time monitoring.
The analyzer's zero-dead-volume hygienic measurement cells in multiple wetted materials enable fast response inline monitoring, while its high-resolution continuous measurement with 10 Hz sampling provides real-time data for process control.
South Fork Instruments announced the availability of the Kemtrak UV Spectra on December 04, 2025. To learn more about the analyzer or discuss configuration options, visit www.southforkinst.com or contact South Fork Instruments directly.
The analyzer is designed for real-time absorbance measurement of proteins, peptides, polypeptides, mRNA/DNA, amino acids, APIs (active pharmaceutical ingredients), and process intermediates in bioprocessing and industrial applications.
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