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FAQ: Stress Cardiac MRI for Improved Angina Diagnosis and Treatment
TL;DR
Stress cardiac MRI provides a diagnostic advantage by identifying microvascular angina in patients with clear angiograms, enabling targeted treatment and improved outcomes.
Stress cardiac MRI measures blood flow to detect small vessel problems in patients with chest pain despite normal angiogram results, changing diagnoses in 53% of cases.
This approach significantly improves chest pain symptoms and quality of life scores, particularly benefiting women who often have undiagnosed microvascular angina.
About half of chest pain patients with clear arteries actually have microvascular angina, which stress cardiac MRI can detect to guide proper treatment.
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The research found that chest pain may still be angina even when coronary angiogram testing shows the main heart arteries appear clear, and stress cardiac MRI testing uncovered small vessel problems in about half of participants who had prior coronary angiography indicating no obstructive coronary artery disease.
This is significant because about half of all patients with angina who undergo coronary angiogram testing have no obstructive coronary artery disease identified, and stress cardiac MRI can help correctly diagnose microvascular angina, leading to major improvements in chest pain and quality of life.
While coronary angiogram alone may not always explain chest pain, stress cardiac MRI measures blood flow around the heart and can detect small vessel problems that angiograms might miss, providing a functional test of blood flow.
The study was conducted by Professor Colin Berry, M.B.Ch.B., Ph.D., from the University of Glasgow and Golden Jubilee University National Hospital, and was presented at the American Heart Association's Scientific Sessions 2025 in New Orleans.
In the CorCMR trial with 250 adults with chest pain but no blocked coronary arteries, stress cardiac MRI led to more people being correctly diagnosed with microvascular angina and resulted in major improvements in chest pain and quality of life after six months to one year.
Women are more likely to have small vessel angina that otherwise goes unrecognized, making them particularly good candidates for stress cardiac MRI testing when they have chest pain but clear coronary arteries on angiogram.
Microvascular angina involves problems with the small vessels of the heart rather than blockages in the main coronary arteries, which means patients can have real angina symptoms even when their main heart arteries appear wide open on traditional testing.
This study is currently a research abstract presented at a scientific meeting and the findings are considered preliminary until published as a full manuscript in a peer-reviewed scientific journal.
The study involved 250 adults with chest pain but no blocked coronary arteries who were randomly assigned to two groups - one where stress cardiac MRI results were used to guide treatment and one where results were not disclosed, with neither participants nor doctors knowing which group they were in during the study.
Curated from NewMediaWire
