FAQ: IntegrateRNA's Custom Aminoacyl-tRNA In Vitro Synthesis Service

What is the main purpose of IntegrateRNA’s new service?

The service enables the generation of customized aminoacylated tRNAs to support protein synthesis research, particularly for creating proteins with non-canonical amino acids that have enhanced functional characteristics.

Why is this aminoacyl-tRNA synthesis service significant for researchers?

It allows scientists to design and produce custom proteins with improved stability, activity, or specificity that may not be possible through natural processes alone, accelerating biotechnology development in areas like therapeutics and industrial enzymes.

How does the aminoacyl-tRNA synthesis process work?

The service uses a robust in vitro translation system with enzymes to covalently link amino acids to transfer RNA molecules, similar to the natural cellular translation process, enabling high-yield production of aminoacylated tRNAs.

What are the key technical features and innovations of this service?

The technology supports the inclusion of non-canonical or modified amino acids, enabling an expanded design space for researchers and high-yield production of aminoacylated tRNAs using enzyme-based processes.

Which industries and applications will benefit from this service?

The service will benefit pharma R&D, protein engineering, novel biologics development, synthetic biology, drug discovery, and enzyme engineering by enabling the creation of protein variants with unique properties.

Who is offering this aminoacyl-tRNA synthesis service?

IntegrateRNA, a division of Creative Biogene that specializes in providing high-quality oligonucleotides and custom RNA synthesis services for academia, pharma, and biotech research.

What future developments are planned for this service?

IntegrateRNA plans to improve the platform by supporting an even broader array of amino acid modifications and expanding production to industrial scale, which could impact synthetic biology and therapeutic protein development.

How can researchers access more information about this service?

Researchers can visit IntegrateRNA’s Aminoacyl-tRNA In Vitro Synthesis Service page for detailed information about the service.