FAQ: Jupiter Neurosciences' JOTROL Technology and Nugevia Consumer Line Launch
Summary
What is JOTROL and what makes it different from other resveratrol products?
JOTROL is an enhanced orally administered resveratrol formulation that delivers 8-10 times higher blood plasma levels than standard resveratrol with one-tenth the dose, without gastrointestinal side effects, making it therapeutically effective where other products fail.
What therapeutic benefits does JOTROL provide?
JOTROL provides antioxidant and anti-inflammatory effects, activates PARP-1 for DNA repair and stress response, improves cardiovascular health, enhances cognitive function, and has antibacterial and antiviral properties against food-borne pathogens.
Why is Jupiter Neurosciences launching a consumer product line called Nugevia?
The company launched Nugevia to leverage their clinically proven JOTROL technology in the growing longevity market, generate cash flow for their biotech operations, and provide consumers with supplements backed by actual clinical data.
What are the three initial Nugevia formulations and what do they target?
Nugevia’s first three formulations target mitochondrial support, mental clarity, and ‘beauty from within,’ with Nugevia GLO specifically designed to support radiant skin through cellular defense, collagen integrity, and hydration.
How does JOTROL achieve therapeutic plasma concentrations without side effects?
Through reformulation and clinical trials, JOTROL achieves plasma concentrations over 250 nanograms per milliliter required for therapeutic benefits while avoiding the severe gastrointestinal side effects associated with high doses of standard resveratrol.
What medical conditions is Jupiter Neurosciences targeting with JOTROL?
The company is developing JOTROL to treat central nervous system disorders including Alzheimer’s, Parkinson’s, and rare diseases, with a Parkinson’s trial currently underway.
How is Nugevia being sold to consumers?
Nugevia products are sold via a direct-to-consumer (DTC) model, making them easily accessible to consumers interested in longevity and healthspan benefits.
What is the patent protection status for JOTROL?
JOTROL is patented worldwide through 2036, providing the company with extensive intellectual property protection for their innovative formulation.
Why is resveratrol difficult to use therapeutically in its standard form?
Standard resveratrol requires extremely high doses to achieve therapeutic plasma concentrations, which causes severe gastrointestinal side effects or requires swallowing large numbers of oversized pills, making practical use impossible.

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