FAQ: Investing in Small-Cap Biopharma Companies Innovating in Pain Therapy

What is the projected growth of the transdermal patch market by 2030?

The transdermal patch market is projected to grow from $7.8 billion in 2023 to nearly $10.95 billion by 2030, with pain patches expected to increase from $4.8 billion in 2021 to $7.3 billion by 2031.

Why is transdermal drug delivery considered important?

Transdermal drug delivery is important because it offers a safer alternative to traditional opioid use, manages chronic pain in aging populations, and delivers medications without needles.

What is Nutriband Inc.’s lead product candidate?

Nutriband Inc.’s lead product candidate is AVERSA Fentanyl, a transdermal patch designed to deter abuse, misuse, and accidental exposure in opioid pain management.

How does Nutriband Inc. generate revenue currently?

Nutriband Inc. generates revenue through its Pocono Pharma subsidiary, which produces kinesiology tape sold in retail giants like Walmart, Walgreens, Target, and CVS, recording $667 thousand in revenue in the first quarter of 2025.

What is the significance of Nutriband’s AVERSA technology?

Nutriband’s AVERSA technology leverages an aversive agent coating to address the most common form of fentanyl patch abuse—oral consumption, aligning with the FDA’s Opioids Action Plan for safer opioid use.

What are the next steps for AVERSA Fentanyl’s development?

The next steps include filing an Investigational New Drug application with the FDA and preparing for a human abuse liability clinical study, pursuing the 505(b)(2) pathway for a faster route to market.

How is Nutriband’s AVERSA platform protected?

Nutriband’s AVERSA platform is protected by a broad international IP portfolio with patents issued in 46 countries, including a US patent granted in June 2025 for its transdermal abuse-deterrent system.

What does Nutriband’s inclusion in Russell indexes signify?

Nutriband’s inclusion in the Russell Microcap, Russell Microcap Growth, Russell 3000E, and Russell 3000E Growth indexes signals growing institutional awareness and progress toward building shareholder value.